April 26th April 27th Symposium News April 21, 2005 JESSE BLOUT Executive Director, Mayor's Office of Workforce and Economic Development to speak at the symposium on April 26 March 25, 2005 PRESS MENTION Ny Teknik: "Sverige söker stamcellsam- arbete med USA" March 22, 2005 ROBERT KLIEN Chairman of the CIRM to speak at the symposium on April 26 March 15, 2005 PRESS MENTION Svenska Dagbladet: "Stamceller hett i Kalifornien"

7:30 AM REGISTRATION AND COFFEE 8:25 AM OPENING REMARKS Barbro S. Osher, Consul General of Sweden in San Francisco (5 min). 8:30 AM INTRODUCTION - SPECIAL APPEARANCE Jesse Blout, Executive Director, Mayor's Office of Workforce and Economic Development (15 min). 8:45 AM INTRODUCTION - SPECIAL APPEARANCE Robert Klein, Chairman the California Institute of Regenerative Medicine (30 min). 9:15 AM INVESTING IN STEM CELLS COMPANIES Panel Discussion #1. Participants: Deepa Pakianahthan, Ph.D., (Principal, Delphi Ventures), Andy Schwab (Managing Partner, 5AM Ventures) and Sylvia Burks (Swedish Practice Team, Pillsbury Winthrop Shaw Pittman, LLP) (45 min). 10:00 AM COFFEE BREAK (15 min) 10:15 AM LEGAL PERSPECTIVES & CALIFORNIA PROPOSITION 71 AND ITS SIGNIFICANCE Panel Discussion #2. Participants: Maureen Corcoran, (Leader Healthcare Industry Team, Pillsbury Winthrop Shaw Pittman LLP) on Prop. 71 (15 min), John Wetherell, Ph.D. (Steering committee, National Life Science Group, Pillsbury Winthrop Shaw Pittman LLP) on registration, licensing and Intellectual Property (IP) issues in cross border transactions as well as stem cells companies set-up and structure (45 min). 11:15 AM KEYNOTE SPEAKER Arnold R. Kriegstein, MD, Ph.D., (Director, Program in Developmental and Stem Cell Biology, UCSF School of Medicine). Title: "Developmental Biology As The Foundation For Stem Cell Research" (45 min). 12:00 PM LUNCH BREAK (60 min) 1:00 PM KEYNOTE SPEAKER Henrik Semb, Ph.D., (Professor, Lund University and Co-founder, Cellartis). Title: "Human Embryonic Stem Cells-Future Potential in Curative Medicine with Diabetes as an Example" (45 min). 1:45 PM STEM CELLS BUSINESS IN SWEDEN Anders Vedin, MD, Ph.D, (Vedicon Consultancy; Chairman, Cellartis). Title: "Commercialization Of Radical Bio-Medical Innovation - Opportunity And Risk: The Case Of Human Embryonic Stem Cells" (15 min). Anders Haegerstrand, M.D., Ph.D., (Vice President and Chief Scientific Officer, Neuronova). Title: "Pioneering Therapeutic Neurogenesis, Idea to Proof-of-Concept" (15 min). 2:15 PM STEM CELLS BUSINESS IN THE UNITED STATES Jane Lebkowski, Ph.D., (Senior Vice-President of Tissue Regenerative Medicine, Geron Corporation). Title: "Development of Human Embryonic Cell Based Therapeutics for the Treatment of Human Degenerative Diseases" (45 min), Ralph Snodgrass, Ph.D., (CEO, VistaGen Therapeutics, Inc.). Title: "Embryonic Stem Cells: Powerful New Tools for Drug Discovery and Development" (30 min). 3:30 PM COFFEE BREAK (15 min) 3:45 PM CASE STUDY - STEM CELLS INC. Irving L. Weissman, M.D., (Professor of Cancer Biology and Professor of Biological Sciences and Founder, Stem Cells Inc.) (30 min) 4:15 PM SWEDISH-CALIFORNIAN BUSINESS OPPORTUNITIES Panel Discussion #3. Participants: Anders Vedin, MD, Ph.D., (Vedicon Consultancy; Chairman, Cellartis), Ralph Snodgrass, Ph.D., (CEO Vistagen Inc), Anders Haegerstrand, M.D., Ph.D., (Vice President and Chief Scientific Officer, Neuronova) and Jane Lebkowski, Ph.D., (Senior Vice-President of Tissue Regenerative Medicine, Geron Corporation) (45 min). 5:00 PM RECAP AND CONCLUSIONS OF BUSINESS TRACK (30 min). 6:30 PM RECEPTION 7:30 PM DINNER Welcome by Nils Welin, Executive Director of The Swedish-American Chamber of Commerce in San Francisco/Silicon Valley. 9:00 AM INTRODUCTION Introduction to the scientific and medical benefits of stem cells by co-organizers Kent Persson, Ph.D., (Scientific Director, Astragen LLC) and Neerja Sethi, Ph.D., (CEO, Astragen LLC) (10 min). 9:15 AM SPEAKER David Warburton, D.Sc., M.D., (Prof., USC Keck School of Medicine and School of Dentistry, Leader, Developmental Biology Program, Children's Hospital Los Angeles, Saban Research Institute). . Title: "Stem cells In Organ Repair And Regeneration" (15 min). 9:30 AM KEYNOTE SPEAKER Anders Björklund, M.D., Ph.D., (Wallenberg Neuroscience Center, Division of Neurobiology, Lund University). Title: "Use Of Stem Cells For Cell Replacement Therapy In Parkinson's Disease" (45 min). 10:15 AM COFFEE BREAK (30 min) 10:45 AM SPEAKER Renee A. Reijo Pera, Ph.D., (Co-director, Program in Human Stem Cell Biology, UCSF). Title: "Human Embryonic Stem Cell-Derived Germ Cells" (15 min). 11:00 AM KEYNOTE SPEAKER Sten Eirik W. Jacobsen, M.D., Ph.D., (Prof. of Stem Cell Biology, Head of Hematopoietic Stem Cell Laboratory, Director of Lund Stem Cell Center, Lund University). Title: "Role of Cytokines in Regulation of Hematopoietic Stem Cell Fate and Blood Lineage Development" (45 min). 11:45 AM APPLIED BIOSYSTEMS William M. Strauss, M.D.,(Assistant Professor, University of Colorado at Boulder). Title: "Is There a Role for Non-Coding RNAs in the Lineage Restriction of the Early Embryo?" (30 min) 12:15 PM LUNCH BREAK (60 min) 1:15 PM KEYNOTE SPEAKER Lars Ährlund-Richter, PhD, Prof., Clinical Research Centre, Karolinska Institutet. Title: "Challenges For Achieving Clinically Eligible Cells" (45 min). 2:00 PM SPEAKER Outi Hovatta, Ph.D., (Prof., Karolinska Institute, Department of Clinical Science, Division of Obstetrics and Gynaecology, Huddinge University Hospital). Title: "Derivation of Human Embryonic Stem Cells Lines" (15 min). 2:15 PM SPEAKER Susan Fisher, Ph.D., (Prof., Department of Cell and Tissue Biology, University of California San Francisco). Title: "Polarity as an Important Determinant of 'Stemness'" (15 min). 2:30 PM CHALLENGES TOWARDS CLINICAL APPLICATIONS OF STEM CELLS Panel Discussion #4. Participants: Susan Fisher, Ph.D., (University of California San Francisco), Bertram H. Lubin, M.D., (Children's Hospital of Oakland Research Institute), Anders Björklund, M.D., PhD., (Lund University) and Henrik Semb, Ph.D., (Lund University and Cellartis) (30-45 min). 3:15 PM COFFEE BREAK (30 min) 3:45 PM SPEAKER Ernest Arenas, M.D., Ph.D., (Prof., Laboratory of Molecular Neurobiology, Karolinska Institute). . Title: "Engineering a Dopaminergic Phenotype in Stem Cells" (15 min). 4:00 PM SPEAKER Rik Derynck, Ph.D., (Prof., Department of Cell and Tissue Biology Director, Program in Craniofacial and Mesenchymal Biology, University of California San Francisco). Title: "TGF-Beta Family Signaling in Mesenchymal Differentiation" (15 min). 4:15 PM SPEAKER Michael German, M.D., (Prof., University of California San Francisco Diabetes Center), . Title: "Insulin Production From Stem Cells for the Treatment of Diabetes". (15 min). 4:30 PM RECAP AND CONCLUSION OF SCIENCE TRACK and CLOSING REMARKS (30 min) Organizers will facilitate private discussions upon request. Interested parties are encouraged to contact Symposium representatives with requirements and/or assistance in finding suitable contacts. Match-Making opportunities will be scheduled at Symposium venue but separate from regular programming. For additional information and/or arrangements please contact Kent Persson or Hugo Hammar on kent.persson@astragen.com and hugo.hammar@sacc-sf.org respectively. Download the program (Adobe PDF format)